For the most recent publication listing, please visit PubMed
(lab members highlighted in bold; ‡ indicates corresponding author)

– 2024 –

Mellouk A, Jaouen PL, Ruel LJ, Lê M, Martini C, Moraes TF, El Bakkouri M, Lagüe P, Boisselier E, Calmettes C (2024) POTRA domains of the TamA insertase interact with the outer membrane and modulate membrane properties. PNAS DOI:10.1073/pnas.2402543121.

Tran TTQ, Narayanan C, Loes AN, Click TH, Pham NTH, Létourneau M, Harms MJ, Calmettes C, Agarwal PK, Doucet N (2024) Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonuclease. J Biol Chem DOI: 10.1016/j.jbc.2024.107280.

Martini C, Araba V, Beniani M, Armoa Ortiz P, Simmons M, Chalbi M, Mellouck A, El Bakkouri M, Calmettes C (2024) Unraveling the crystal structure of the HpaA adhesin: Insight into cell adhesion function and epitope localization of a Helicobacter pylori vaccine candidate. mBio DOI: 10.1128/mbio.02952-23.

– 2022 –

Bourgade K, Frost EH, Dupuis G, Witkowski JM, Laurent B, Calmettes C, Ramassamy C, Desroches M, Rodrigues S, Fülöp T (2022) Interaction Mechanism Between the HSV-1 Glycoprotein B and the Antimicrobial Peptide Amyloid-β. J Alzheimers Dis Rep. DOI: 10.3233/ADR-220061

Said F, Mahanta U, Panda A, Mezzo A, Jolivet NY, Bitazar R, John G, Martinez M, Mellouk A, Calmettes C, Chang YW, Sharma G, Islam ST (2022) Bacterial Outer Membrane Polysaccharide Export (OPX) Proteins Occupy Three Structural Classes with Selective β-Barrel Porin Requirements for Polymer Secretion. Microbial Spectr. DOI: 10.1128/spectrum.01290-22

– 2021 –

Pham NTH, Létourneau M, Fortier M, Bégin G, Al-Abdul-Wahid MS, Pucci F, Folch B, Rooman M, Chatenet D, St-Pierre Y, Lagüe P, Calmettes C, Doucet N (2021) Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7J Biol Chem. doi: 10.1016/j.jbc.2021.101308

– 2020 –

Narayanan C, Bernard DN, Létourneau M, Gagnon J, Gagné D, Bafna K, Calmettes C, Couture JF, Agarwal PK, Doucet N (2020) Insights into structural and dynamical changes experienced by human RNAse 6 upon ligand bindingBiochemistry doi: 10,1021/acs.biochem.9b00888

– 2019 –

El Bakkouri M, Kouidmi I, Wernimont AK, Amani A, Hutchinson A, Loppnau P, Kim JJ, Flueck C, Seitova A, Senisterra G, Kakihara Y, Kim C, Blackman MJ, Calmettes C, Baker DA, Hui R (2019) Structure of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activationPNAS doi: 10.1073/pnas.1905558116

Fegan JE, Calmettes C, Islam EA, Ahn SH, Chaudhuri S, Yu RH, Gray-Owen SD, Moraes TF, Schryvers AB (2019) Utility of hybrid transferrin binding protein antigens for protection against pathogenic Neisseria speciesFrontiers in Immunology doi: 10.3389/fimmu.2019.00247

– 2018 –

Babu M*, Bundalovic-Torma C*, Calmettes C*, Phanse S, Jiang Y, Deineko V, Mehla J, Vastermark A, Kagan O, Pogoutse O, Gagarinova A, Kumar A, Guo H, Minic Z, Aoki H, Holtzapple E, Zhang Z, Pandya Y, Lai CCL, Leung E, El Bakkouri M, Hooda Y, Shah M, Vlasblom J, Greenblatt JF, Rajagopala SV, Wutchy S, Houry W, Saier M, Uetz P, Moraes TF, Parkinson J, Emili A (2018) Global landscape of membrane protein complexes in Escherichia coli. Nature Biotechnology 10.1038/nbt.4024 (* equal contribution)

– 2017 –

Pawluk A, Shah M., Mejdani M, Calmettes C, Moraes TF, Davidson A, Maxwell K. (2017) Disabling a type I-E CRISPR-Cas nuclease with a bacteriophage-encoded anti-CRISPR protein. mBio 10.1128/mBio.01751-17

– 2016

McCallum M, Tammam S, Little DJ, Robinson H, Koo J, Shah M, Calmettes C, Moraes TF, Burrows LL, Howell PL (2016) Disabling a type I-E CRISPR-Cas nuclease with a bacteriophage-encoded anti-CRISPR protein. J Biol Chem. 291:11003-15


Calmettes C, Ing C, Buckwalter CM, El Bakkouri M, Chieh-Lin Lai C, Pogoutse A, Gray-Owen SD, Pomès R, Moraes TF (2015) The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD. Nature Communications 6:7996

Calmettes C, Judd A, Moraes TF (2015) Structural Aspects of Bacterial Outer Membrane Protein Assembly. Adv Exp Med Biol. 883:255-70

Sit B, Crowley SM, Bhullar K, Lai CC, Tang C, Hooda Y, Calmettes C, Khambati H, Ma C, Brumell JH, Schryvers AB, Vallance BA, Moraes TF (2015) Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen. Plos Pathog. 11:e1005107

Adamiak P*, Calmettes C*, Moraes TF, Schryvers AB (2015) Patterns of structural and sequence variation within isotype lineages of the Neisseria meningitidis transferrin receptor system. Microbiologyopen 4:491-504 (* equal contribution)

Frandoloso R*, Martínez-Martínez S*, Calmettes C*, Fegan J, Costa E, Curran D, Yu RH, Gutiérrez-Martín CB, Rodríguez-Ferri EF, Moraes TF, Schryvers AB (2015) Nonbinding site-directed mutants of transferrin binding protein B exhibit enhanced immunogenicity and protective capabilities. Infect Immun. 83:1030-8 (* equal contribution)


Shnitsar V, Li J, Li X, Calmettes C, Basu A, Casey JR, Moraes TF, Reithmeier RA (2013) A substrate access tunnel in the cytosolic domain is not an essential feature of the solute carrier 4 (SLC4) family of bicarbonate transporters. J Biol Chem. 288:33848-60

El Bakkouri M, Rathore S, Calmettes C, Wernimont AK, Liu K, Sinha D, Asad M, Jung P, Hui R, Mohmmed A, Houry WA (2013) Structural insights into the inactive subunit of the apicoplast-localized caseinolytic protease complex of Plasmodium falciparum. J Biol Chem. 288:1022-31


Silva LP, Yu RH, Calmettes C, Yang X, Moraes TF, Schriemer DC, Schryvers AB (2012) Steric and allosteric factors prevent simultaneous binding of transferrin-binding proteins A and B to transferrin. Biochem J. 444:189-97

Calmettes C, Alcantara J, Yu RH, Schryvers AB, Moraes TF (2012) The structural basis of transferrin sequestration by transferrin-binding protein B. Nature Stuctural & Molecular Biology. 19:358-60


Yang X, Yu RH, Calmettes C, Moraes TF, Schryvers AB (2011) Anchor peptide of transferrin-binding protein B is required for interaction with transferrin-binding protein A. J Biol Chem. 286:45165-73

Silva LP, Yu R, Calmettes C, Yang X, Moraes TF, Schryvers AB, Schriemer DC (2011) Conserved interaction between transferrin and transferrin-binding proteins from porcine pathogens. J Biol Chem. 286:21353-60

Calmettes C, Yu RH, Silva LP, Curran D, Schriemer DC, Schryvers AB, Moraes TF (2011) Structural variations within the transferrin binding site on transferrin-binding protein B, TbpB. J Biol Chem. 286:12683-92